| 产品详情 |
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| Antigenic Specificity | ADAM10 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 0.25-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ADAM10 Polyclonal Antibody. Proinflammatory cytokine tumor necrosis factor-a (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and des |
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| Immunogen | n/a |
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| Other Names | AD10, HsT18717, MADM, kuz, CDw156 |
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| Gene, Accession # | Entrez: 102, 11487, 29650; Uniprot: O14672, O35598, Q10743 |
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| Catalog # | PA1-12500 |
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| Price | |
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| Order / More Info | ADAM10 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 20363245 |
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