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| Antigenic Specificity | ADAM17 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ADAM17 Polyclonal Antibody. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. |
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| Immunogen | n/a |
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| Other Names | A disintegrin and metalloproteinase domain 17, TNF-alpha-converting enzyme, TNF-alpha convertase, Snake venom-like protease, CD156b antigen, CSVP, TACE |
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| Gene, Accession # | Entrez: 11491, 57027, 6868; Uniprot: P78536, Q9Z0F8, Q9Z1K9 |
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| Catalog # | PA5-27395 |
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| Price | |
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| Order / More Info | ADAM17 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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