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| Antigenic Specificity | CaBP8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:200-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CaBP8 Polyclonal Antibody. Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family |
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| Immunogen | n/a |
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| Other Names | CABP8; calcium-binding protein 8; calcium-binding protein CABP8; calneuron I; calneuron-1 |
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| Gene, Accession # | Entrez: 83698; Uniprot: Q9BXU9 |
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| Catalog # | PA5-57592 |
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| Price | |
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| Order / More Info | CaBP8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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