| 产品详情 |
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| Antigenic Specificity | CRTH2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CRTH2 Polyclonal Antibody. The chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) is a recently identified receptor for the prostaglandin D2 (PGD2) in addition to the classic prostaglandin D receptor. CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo. At lea |
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| Immunogen | n/a |
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| Other Names | CD294, CRTH2, DL1R, DP2, GPR44, G protein-coupled receptor 44, G Protein-Coupled Rec. 44 |
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| Gene, Accession # | Entrez: 11251, 14764, 19214, 309212, 498475, 5729; Uniprot: P70263, Q13258, Q6XKD3, Q9R261, Q9Y5Y4, Q9Z2J6 |
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| Catalog # | PA5-20333 |
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| Price | |
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| Order / More Info | CRTH2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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