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| Antigenic Specificity | LIME |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: Assay dependent. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LIME Polyclonal Antibody. LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation. |
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| Immunogen | n/a |
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| Other Names | Lck-interacting molecule |
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| Gene, Accession # | Entrez: 54923; Uniprot: Q9H400 |
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| Catalog # | PA1-35994 |
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| Price | |
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| Order / More Info | LIME Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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