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| Antigenic Specificity | Cyclin B1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:25, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin B1 Polyclonal Antibody. Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs). Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis. Destruction of Cyclin B1 is required for cell cycle progression |
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| Immunogen | n/a |
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| Other Names | Ccnb1;Ccn-2; Ccnb1-rs13; Cycb; Cycb1; G2/mitotic-specific cyclin-B1 |
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| Gene, Accession # | Entrez: 268697; Uniprot: P24860 |
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| Catalog # | PA5-35245 |
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| Price | |
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| Order / More Info | Cyclin B1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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