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Product Name | Human CellExp™ IL-10, Human Recombinant |
Description | IL10 is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. MW: 17 kDa, non-disulfide bonded homodimer, glycosylated. Purity > 95% |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor. |
Gene, Accession, CAS # | IL10, Gene ID: 3586, Accession: P22301 |
Catalog # | 6466-50 |
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Order / More Info | Human CellExp™ IL-10, Human Recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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