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| Product Name | Human CellExp™ IL-15 R alpha / CD215, Fc Tag, Human recombinant |
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| Description | Purity >95%. This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.8 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures. |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL15RA, IL-15RA, IL-15R-alpha, IL-15 receptor subunit alpha |
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| Gene, Accession, CAS # | IL15RA, Gene ID: Q13261, Accession: Q13261 |
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| Catalog # | P1424-50 |
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| Order / More Info | Human CellExp™ IL-15 R alpha / CD215, Fc Tag, Human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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