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Product Name | (S)-Duloxetine hydrochloride |
Description | High affinity, competitive 5-HT and noradrenaline (NA) re-uptake inhibitor (Ki values are 8.5 and 45 nM for 5-HT and NA reuptake respectively in cortical synaptosomes; IC50 values are 28 and 46 nM for 5-HT and NA reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki = 300 nM in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable. Purity 99%. MW (observed): 333.88 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride |
Gene, Accession, CAS # | CAS: 136434-34-9 |
Catalog # | 4798/50 |
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Order / More Info | (S)-Duloxetine hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25161814 |
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