| Edit |   |
| Antigenic Specificity | HAP1 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 ug |
| Concentration | n/a |
| Applications | Immunohistochemistry: 3.75 µg/mL, peptide-ELISA: 1:32000, Western Blot: 0.1-0.3 µg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HAP1 Polyclonal Antibody. Huntington's disease , a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins , and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Immunogen | n/a |
| Other Names | HAP1; huntingtin-associated protein 1 (neuroan 1); HAP2; HIP5; HLP; hHLP1; huntingtin-associated protein 1; huntingtin-associated protein 2; neuroan 1 |
| Gene, Accession # | Entrez: 9001; Uniprot: P54257 |
| Catalog # | PA5-18616 |
| Price | |
| Order / More Info | HAP1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |