| 产品详情 |
| Edit |   |
|---|
| Product Name | GSK591 |
|---|
| Description | Purity >95%. GSK591 is a chemical probe for protein arginine methyltransferase 5 (PRMT5) that potently inhibits the PRMT5/MEP50 complex from methylating histone H4 (IC50 = 11 nM) in vitro . GSK591 is selective for PRMT5 (up to 50 µM) relative to a panel of other methyltransferases. In Z-138 cells, GSK591 inhibits the symmetric arginine methylation of SmD3 with an EC50 value of 56 nM. See the Structural Genomics Consortium (SGC) website for more information. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-4-pyridinecarboxamide, EPZ015866, GSK3203591 |
|---|
| Gene, Accession, CAS # | CAS: 1616391-87-7 |
|---|
| Catalog # | LS-H8024 |
|---|
| Price | |
|---|
| Order / More Info | GSK591 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|