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Product Name | Activin A, Recombinant, Human/Mouse/Rat, aa311-426 (Activin A GMP, INHBA) |
Description | Purity ~97% (SDS-PAGE). Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. Activin isoforms and other members of the TGF-beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits. Five beta subunits (mammalian beta A, beta B, beta C, beta E and Xenopus beta D) have been cloned to date. The activin/inhibin nomenclature reflects the subunit co |
Size | 10ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | SwissProt: P08476 |
Catalog # | 145698 |
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Order / More Info | Activin A, Recombinant, Human/Mouse/Rat, aa311-426 (Activin A GMP, INHBA) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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