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Product Name | IL-12p80, Human Recombinant |
Description | IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or can form a homodimer designated as IL-12 p80. Elevated levels of IL-12 p80 are correlated with macrophage recruitment and increased inflammation in asthma and respiratory viral infection models. Recombinant human IL-12 p80 is an 80.0 kDa disulfide linked homodimer consisting of two p40 chains of IL-12. MW: 80 kDa. Purity ≥95% |
Size | 10 µg |
Concentration | n/a |
Applications | RUO |
Other Names | NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12. |
Gene, Accession, CAS # | IL12B, Gene ID: 3593, Accession: P29460 |
Catalog # | 7104-10 |
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Order / More Info | IL-12p80, Human Recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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