| Edit |   |
|---|
| Antigenic Specificity | PHD2 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | PHD2 Polyclonal Antibody. The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). |
|---|
| Immunogen | n/a |
|---|
| Other Names | HIF prolyl hydroxylase 2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; egl nine homolog 1; egl nine-like protein 1; hypoxia-inducible factor prolyl hydroxylase 2; prolyl hydroxylase domain-containing protein 2; zinc finger MYND domain-containing protein 6 |
|---|
| Gene, Accession # | Entrez: 54583; Uniprot: Q9GZT9 |
|---|
| Catalog # | PA5-17050 |
|---|
| Price | |
|---|
| Order / More Info | PHD2 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|