| 产品详情 |
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| Product Name | Ikarugamycin |
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| Description | Purity ~99%. Ikarugamycin is an unsual pentacyclic tetramic acid produced by Streptomyces phaeochromogenes with potent activity against the protozoan, Trichomonas vaginalis, reported in 1972. Ikarugamycin also demonstrated selective Gram positive antibacterial activity and more recently has been shown to exhibit anti-ulcer activity possibly by inhibition of Helicobacter. Investigation of the pharmacology of ikarugamycin has demonstrated a variety of actions including the inhibition of the uptake of oxidized low-density lipoprotein in mouse macrophages, blockade of PMA and Nef-mediated cell surface CD4 down-regulation and inhibition of clathrin-coated pit-mediated endocytosis. Importantly, ikarugamycin is emerging as a useful agent for studying the process of endocytosis. Source: Streptomyces sp. Apperance: White solid Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility. |
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| Size | 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I2300-20 |
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| Order / More Info | Ikarugamycin from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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