| 产品详情 |
| Edit |   |
|---|
| Product Name | IkBA Recombinant protein |
|---|
| Description | 1-175. MW: ~46 kDa. Purity >90%. Recombinant human IkBA (1-175) was expressed in E. coli cells using an N-terminal GST tag.Scientific Background: Itheta degree Balpha is an inhibitor of the NFtheta degree B complex and inactivates the NFtheta degree B by trapping it in the cytoplasm (1). Phosphorylation of serine residues on the Itheta degree B protein by Itheta degree B kinases (IKKs) marks it for destruction via the ubiquitination pathway, thereby allowing the activation of the |
|---|
| Size | 0.02 mg, 0.05 mg |
|---|
| Concentration | 0.2ug/ul |
|---|
| Applications | Kinase Assay, Western Blot (WB) |
|---|
| Other Names | [IKBA; NFKBIA; MAD-3; NFKBI; IkappaBalpha Protein; IkBa Protein] |
|---|
| Gene, Accession, CAS # | IkBA, Gene ID: 4792, Accession: NP_065390.1 |
|---|
| Catalog # | MBS515216 |
|---|
| Price | |
|---|
| Order / More Info | IkBA Recombinant protein from MYBIOSOURCE INC. |
|---|
| Product Specific References | 1. Auphan, N. Et al: Immunosuppression by glucocorticoids: inhibition of NF-kappa-B activity through induction of I-kappa-B synthesis. Science 270: 286-290, 1995. 2. Bondeson, J. Et al: Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent. J Rheumatol. 2007 Mar;34(3):523-33. |
|---|
| 产品资料 |
|
|