| 产品详情 |
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| Antigenic Specificity | Transferrin Receptor |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Transferrin Receptor Polyclonal Antibody. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
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| Immunogen | n/a |
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| Other Names | CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1 |
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| Gene, Accession # | Entrez: 22042, 7037; Uniprot: P02786, Q62351 |
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| Catalog # | PA5-27739 |
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| Price | |
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| Order / More Info | Transferrin Receptor Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 28066232 |
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| 产品资料 |
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