| 产品详情 |
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| Antigenic Specificity | Mad |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | ELISA: Assay-dependent, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mad Polyclonal Antibody. MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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| Immunogen | n/a |
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| Other Names | Max dimerization protein 1, Max dimerizer 1, Protein MAD, MXD1, MAD |
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| Gene, Accession # | Entrez: 17119, 362391, 4084; Uniprot: P50538, Q05195 |
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| Catalog # | PA5-79711 |
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| Price | |
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| Order / More Info | Mad Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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