产品详情 |
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Product Name | Ac-VDVAD-AFC |
Description | Purity >95%. Ac-VDVAD-AFC is a fluorogenic substrate whose amino acids VDVAD have been shown to be a preferred cleavage site for caspase-2. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Increases in Ac-VDVAD-AFC cleavage have been reported to correlate with nitric oxide-induced activation of caspase-2 and subsequent apoptosis in human neuroblastoma lines. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-acetyl-L-valyl-L-a-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-a-asparagine, Caspase-2 Substrate (Fluorogenic), N-Acetyl-Val-Asp-Val-Ala-Asp-7-amino-4-Trifluoromethylcoumarin |
Gene, Accession, CAS # | CAS: 210344-94-8 |
Catalog # | LS-H5415 |
Price | |
Order / More Info | Ac-VDVAD-AFC from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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