产品详情 |
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Product Name | Paxilline |
Description | Purity >98%. Paxilline is an indole diterpene from fungi which potently and reversibly inhibits large conductance Ca2+ -activated K+ (BKCa) channels, as shown in patch clamp (Ki = 1.9 nM) and whole smooth muscle cell studies (Ki = 35.7 nM). It also enhances the binding of charybdotoxin, a peptidyl neurotoxin, to BKCa channels. Paxilline is currently used to evaluate the role of BKCa channels in various cell processes and responses. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 5,6,6a,7,12,12bS,12cR,13,14,14aS-decahydro-4bS-hydroxy-2R-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-2H-1-benzopyrano[5',6':6,7]indeno[1,2-b]indole-3(4bH)-one |
Gene, Accession, CAS # | CAS: 57186-25-1 |
Catalog # | LS-H9279 |
Price | |
Order / More Info | Paxilline from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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