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| Antigenic Specificity | MIB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:20-1:100, Immunofluorescence: 1:20-1:100, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MIB1 Polyclonal Antibody. MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis. |
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| Immunogen | n/a |
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| Other Names | E3 ubiquitin-protein ligase MIB1; Mind bomb homolog 1; DAPK-interacting protein 1; DIP-1; Zinc finger ZZ type with ankyrin repeat domain protein 2; MIB1; DIP1; KIAA1323; ZZANK2 |
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| Gene, Accession # | Entrez: 57534; Uniprot: Q86YT6 |
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| Catalog # | PA5-12069 |
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| Price | |
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| Order / More Info | MIB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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