| 产品详情 |
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| Product Name | Fibroblast Growth Factor 6 (FGF6) (AA 41-208) (Active) protein |
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| Description | Fibroblast Growth Factor-6 (FGF-6) is a cytokine belonging to the heparin-binding FGF family, and is structurally related to other members of FGF family, particularly FGF-4. In vivo, FGF-6 exhibits an expression profile predominantly restricted tothe myogenic lineage, and it preferentially binds to two of the FGF receptors: FGFR1 and FGFR4. FGF-6 functions in muscle regeneration, myoblast proliferation and migration, and muscle differentiation in a dose-dependent manner. In vivo high concentration of recombinant FGF-6 up-regulates and down-regulates FGFR1 and FGFR4, respectively, as FGFR1 promotes the proliferation while FGFR4 promotes the differentiation in the muscle. Besides its dual function in muscle regeneration, FGF-6 may act as a regulator of bone metabolism as well.Recombinant human Fibroblast Growth Factor-6 (rhFGF-6) produced in E. coli is a single non-glycosylated polypeptide chain containing 169 amino acids. A fully biologically active molecule, rhFGF-6 has a molecular mass of 18.8 kDa analyzed by reducing SDS-PAGE. Synonyms: Fibroblast Growth Factor-6, HBGF-6, HST-2 |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FGF6|hst2|fgf-6|hbgf-6|HBGF-6|HST2|Fgf-6|HSTF-2|fgf4|fgf6 |
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| Gene, Accession, CAS # | Gene ID: 2251 |
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| Catalog # | ABIN2017826 |
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| Order / More Info | Fibroblast Growth Factor 6 (FGF6) (AA 41-208) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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