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Product Name | Recombinant Human Androgen receptor (AR), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 62.4kDa. Partial: 551-919aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4 |
Gene, Accession, CAS # | AR, UniProt: P10275 |
Catalog # | RPC20924 |
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Order / More Info | Recombinant Human Androgen receptor (AR), partial from BIOMATIK |
Product Specific References | n/a |
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