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| Product Name | Recombinant Human C-C motif chemokine 14 protein (CCL14) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 17.6kDa. Partial: 109-266aa. tag-Free. Mus musculus (Mouse). Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up-regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL-1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin 33; IL-33; IL33; C9orf26; NKHEV; Interleukin-1 family member 11; DVS27; NF-HEV and IL- 1F11 |
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| Gene, Accession, CAS # | Il33, UniProt: Q8BVZ5 |
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| Catalog # | RPC26871 |
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| Order / More Info | Recombinant Human C-C motif chemokine 14 protein (CCL14) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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