| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human C-C motif chemokine 26 protein (CCL26) (Active) |
|---|
| Description | Purity > 95% as determined by SDS-PAGE. MW: 46.9kDa. Heterodimer: 31-96aa & 49-162aa. C-terminal FC-tagged. Homo sapiens (Human). IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL-15RA with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | IL15RA&IL15; Interleukin-15; IL-15; IL15; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin-15 receptor subunit alpha |
|---|
| Gene, Accession, CAS # | IL15 & IL15RA, UniProt: Q13261 & P40933 |
|---|
| Catalog # | RPC26913 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human C-C motif chemokine 26 protein (CCL26) (Active) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|