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| Product Name | Recombinant Human C-C motif chemokine 4 protein (CCL4) (Active) |
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| Description | Purity > 96% as determined by SDS-PAGE and HPLC. MW: 7.8kDa. Full Length of Mature Protein: 24-92aa. tag-Free. Homo sapiens (Human). Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B. {ECO:0000269|PubMed:10540332, ECO:0000269|PubMed:12070155, ECO:0000269|PubMed:8525373}. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | G-26 T-lymphocyte-secreted protein, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta1-69, |
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| Gene, Accession, CAS # | CCL4,LAG1,MIP1B,SCYA4, UniProt: P13236 |
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| Catalog # | RPC26588 |
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| Order / More Info | Recombinant Human C-C motif chemokine 4 protein (CCL4) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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