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| Product Name | Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) protein |
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| Description | Human MIP-4/CCL18 CCL18, is a novel CC chemokine that is highly homologous to MIP-1alpha (61% amino acid sequence identity). CCL18 cDNA encodes an 89 aa residue precursor protein with a 20 aa putative signal peptide that is cleaved to generate a 69 aa residue mature protein which lacks potential glycosylation sites. In vitro, CCL18 mRNA expression is induced in alternatively activated macrophages by Th2 cytokines such as IL-4, IL-10 and IL-13, and inhibited by IFN-gamma. CCL18 mRNA is also expressed by GM-CSF/IL-4-induced monocyte-derived dendritic cells. In vivo, CCL18 is highly expressed in lung and placenta but is not expressed in epidermal Langerhans cells. Recombinant CCL18 has been shown to chemoattract naive T cells, but not monocytes or neutrophils. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AMAC-1|AMAC1|CKb7|DC-CK1|DCCK1|MIP-4|PARC|SCYA18 |
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| Gene, Accession, CAS # | Gene ID: 6362 |
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| Catalog # | ABIN1540325 |
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| Order / More Info | Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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