| 产品详情 |
| Edit |   |
| Antigenic Specificity | ICAM-1 |
| Clone | 1H4 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | fluorescein (FITC) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry: 20 µL x 100 µL whole blood or 10^6 cells |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ICAM-1 Monoclonal Antibody (1H4), FITC. CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
| Immunogen | n/a |
| Other Names | BB2, P3.58, ICAM-1, cell surface glycoprotein P3.58, intercellular adhesion molecule 1, human rhinovirus receptor, major group rhinovirus receptor |
| Gene, Accession # | Entrez: 3383; Uniprot: P05362 |
| Catalog # | MA1-19616 |
| Price | |
| Order / More Info | ICAM-1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | PubMed: 20336056, 21384185 |
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