| 产品详情 |
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| Antigenic Specificity | DMTF1 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | peptide-ELISA: 1:8000, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DMTF1 Polyclonal Antibody. This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic |
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| Immunogen | n/a |
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| Other Names | cyclin D binding myb-like transcription factor 1, DMP1, DMTF, hDMP1, cyclin D-binding Myb-like protein, cyclin-D-binding Myb-like transcription factor 1, cyclin-D-interacting Myb-like protein 1, hDMTF1 |
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| Gene, Accession # | Entrez: 114485, 23857, 9988; Uniprot: Q66HG1, Q8CE22, Q9Y222 |
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| Catalog # | PA5-37917 |
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| Price | |
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| Order / More Info | DMTF1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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