| 产品详情 |
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| Antigenic Specificity | Phospho-GRK2 (Ser670) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-GRK2 (Ser670) Polyclonal Antibody. GRK2 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. |
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| Immunogen | n/a |
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| Other Names | BETA-ARK1, GRK2, ADRBK1, adrenergic, beta, receptor kinase 1, BARK1 |
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| Gene, Accession # | Entrez: 156; Uniprot: P25098 |
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| Catalog # | PA5-77851 |
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| Price | |
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| Order / More Info | Phospho-GRK2 (Ser670) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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