| 产品详情 |
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| Antigenic Specificity | SLP76 |
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| Clone | SLP-76/03 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, porcine |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SLP76 Monoclonal Antibody (SLP-76/03). SLP76 (SH2 domain-containing leukocyte protein of 76 kDa) is a cytosolic adaptor protein which translocates to the plasma mambrane and is involved in multiple signaling pathways in T cells, mast cells, neutrophils and platelets; B cells express its analog SLP65/BLNK (B cell linker protein). SLP76 is phosphorylated by Syk-family and Tec-family tyrosine kinases and couples them to the phosphorylation and activation of PLC-gamma. Via Gads or Grb2, SLP76 also associates with LAT adaptor by involvement of SLP76 proline-rich region. The SH2 domain of SLP76 has been identified as the region involved in binding the serine/threonine kinase HPK1. HPK1 may act as both a positive and a negative regulator by promot |
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| Immunogen | n/a |
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| Other Names | LCP2 |
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| Gene, Accession # | Entrez: 100511843, 16822, 3937; Uniprot: Q13094, Q60787 |
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| Catalog # | MA1-19369 |
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| Price | |
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| Order / More Info | SLP76 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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