| 产品详情 |
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| Antigenic Specificity | FK506 |
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| Clone | FK1 |
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| Host Species | Mouse |
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| Reactive Species | n/a |
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| Isotype | IgM |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay dependent, Western Blot: Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FK506 Monoclonal Antibody (FK1). Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent. [National Center for Biotechnology Information. PubChem Compound Database; CID=445643] |
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| Immunogen | n/a |
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| Other Names | Fujimycin; Tacrolimus; FK-506; C44H69NO12 |
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| Gene, Accession # | n/a |
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| Catalog # | MA1-90186 |
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| Price | |
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| Order / More Info | FK506 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11916981, 16286508, 16597703 |
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| 产品资料 |
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