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Product Name | Serabelisib |
Description | Serabelisib is a potent inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC50 = 15 nM for PI3Kα vs. >1 µM for other isoforms, as well as for mTOR). MLN1117 inhibits AKT phosphorylation and growth in PIK3CA mutant breast cancer cells with IC50 values around 2 µM, yet has no effect on cells lacking PTEN. MW: 363.34. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [6-(2-amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinyl-methanone; MLN1117, INK1117, TAK-117) |
Gene, Accession, CAS # | CAS: 1268454-23-4 |
Catalog # | B1930-25 |
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Order / More Info | Serabelisib from BIOVISION, INC. |
Product Specific References | n/a |
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