| 产品详情 |
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| Product Name | FAK Inhibitor 14 |
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| Description | Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. MW (observed): 284.01. |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1,2,4,5-Benzenetetramine tetrahydrochloride. Y15, NSC 677249 |
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| Gene, Accession, CAS # | CAS: 4506-66-5 |
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| Catalog # | 3414/50 |
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| Order / More Info | FAK Inhibitor 14 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20071540, 21852242, 23446637, 23681745, 23693126, 24039841, 24089517, 24113189, 24523534, 25973915, 26200861, 26247610, 26501082, 27034160, 27152864, 27978828 |
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