| 产品详情 |
| Edit |   |
| Antigenic Specificity | IRF4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, nonhuman primate, rat |
| Isotype | n/a |
| Format | purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Western Blot: 1:1000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IRF4 Polyclonal Antibody. The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
| Immunogen | n/a |
| Other Names | IRF-4; NF-EM5; lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1 |
| Gene, Accession # | Entrez: 16364, 291100, 3662; Uniprot: Q15306, Q64287 |
| Catalog # | PA5-17254 |
| Price | |
| Order / More Info | IRF4 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 产品资料 |
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