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| Product Name | Ki 8751 |
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| Description | Potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFRα and FGFR-2 (IC50 values range from 40 to 170 nM) but is highly selective over other receptor tyrosine kinases (IC50 > 10000 nM for FGFR-2, EGFR and HGFR). Inhibits VEGF-stimulated proliferation of human umbilical vein endothelial cells (HUVEC) and inhibits tumor growth in vivo; antiangiogenic. Purity 97%. MW (observed): 469.41 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(2,4-Difluorophenyl)-N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea |
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| Gene, Accession, CAS # | CAS: 228559-41-9 |
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| Catalog # | 2542/10 |
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| Price | |
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| Order / More Info | Ki 8751 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21306896 |
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