| 产品详情 |
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| Antigenic Specificity | BCAR3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 20 µg/mL, Immunohistochemistry: 20 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BCAR3 Polyclonal Antibody. Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling. |
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| Immunogen | n/a |
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| Other Names | BCAR3, Breast cancer anti-estrogen resistance 3, NSP2, SH2D3B, AND-34 |
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| Gene, Accession # | Entrez: 29815, 310838, 8412; Uniprot: O75815, Q9QZK2 |
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| Catalog # | PA5-34425 |
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| Price | |
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| Order / More Info | BCAR3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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