| 产品详情 |
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| Antigenic Specificity | BCAR3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BCAR3 Polyclonal Antibody. Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. |
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| Immunogen | n/a |
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| Other Names | Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B, BCAR3, NSP2, SH2D3B, UNQ271/PRO308 |
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| Gene, Accession # | Entrez: 29815, 310838, 8412; Uniprot: O75815, Q9QZK2 |
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| Catalog # | PA5-78858 |
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| Price | |
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| Order / More Info | BCAR3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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