| 产品详情 |
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| Antigenic Specificity | RASA4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RASA4 Polyclonal Antibody. This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | n/a |
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| Other Names | CAPRI; GAPL; Ca2+-promoted Ras inactivator; calcium-promoted Ras inactivator; ras GTPase-activating protein 4; rasGAP-activating-like protein 2 |
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| Gene, Accession # | Entrez: 10156, 288589, 54153; Uniprot: O43374, Q6PFQ7 |
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| Catalog # | PA5-72430 |
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| Price | |
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| Order / More Info | RASA4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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