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| Product Name | 20(S)-Hydroxycholesterol |
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| Description | Allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein; binds at a site distinct from the canonical cyclopamine binding site. Activates Hedgehog (Hh) signaling (EC50 ~ 3μM for induction of Hh reporter gene transcription in in NIH 3T3 cells). Induces Smo accumulation in primary cilia; also exhibits osteogenic activity and activates the liver X receptor (LXR). Purity 95%. MW (observed): 402.65 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3β)-Cholest-5-ene-3,20-diol |
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| Gene, Accession, CAS # | CAS: 516-72-3 |
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| Catalog # | 4474/10 |
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| Price | |
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| Order / More Info | 20(S)-Hydroxycholesterol from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22231273 |
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