| 产品详情 |
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| Antigenic Specificity | Cullin 2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 0.1-1.0 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Immunoprecipitation: 2-3 µg/mL, Western Blot: 1:250-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cullin 2 Polyclonal Antibody. CUL-2 is a member of the family of human cullin genes (CUL-1, -2, -3, -4a, -4b, and -5), homologous to the S. cerevisiae cdc53 gene. CUL-1 forms a complex with human p19skp1 and F box protein p45skp2. Together with cdc53 (Known as CulA), as three subunits, they form a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL-1, CUL-2 does not associate with p19skp1 and p45skp2. Instead, CUL-2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown. |
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| Immunogen | n/a |
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| Other Names | CUL-2 |
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| Gene, Accession # | Entrez: 361258, 71745, 8453; Uniprot: Q13617, Q9D4H8 |
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| Catalog # | 51-1800 |
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| Price | |
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| Order / More Info | Cullin 2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15824109, 16261165, 19339690, 21463634, 21778237, 22013077, 22466964, 22537386, 23398456, 25425648, 27031283, 27784791 |
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