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| Antigenic Specificity | SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.Subcellular location: Cytoplasm. Cell junction ?? synapse ?? postsynaptic cell membrane ?? postsynaptic density. Cell junction ?? synapse. Note: Postsynaptic density of neuronal cells.Tissue specificity: Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus. Isoform 2 seems to be expressed ubiquitously. Also known as: SHAN1, SH3 and multiple ankyrin repeat domains protein 1, Somatostatin receptor-interacting protein, SSTR-interacting protein, SSTRIP. |
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| Immunogen | A synthetic peptide from PDZ region of human SHANK1 (Somatostatin receptor-interacting protein) conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 90% identity with rat sequence. |
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| Other Names | SPANK-1|SSTRIP|synamon|Shank1a|Spank1|Sstrip |
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| Gene, Accession # | Gene ID: 50944 |
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| Catalog # | ABIN572129 |
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| Price | |
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| Order / More Info | SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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