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| Product Name | GSK 2606414 |
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| Description | Potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK over HR1 and PKR. Inhibits thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells. Attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Orally bioavailable. Purity 99%. MW (observed): 451.44 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone |
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| Gene, Accession, CAS # | CAS: 1337531-36-8 |
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| Catalog # | 5107/50 |
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| Price | |
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| Order / More Info | GSK 2606414 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 29358734 |
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| 产品资料 |
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