| 产品详情 |
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| Antigenic Specificity | CD41 |
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| Clone | MWReg30 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Description | CD41 Monoclonal Antibody (MWReg30). CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder. |
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| Immunogen | n/a |
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| Other Names | BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B |
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| Gene, Accession # | Entrez: 16399; Uniprot: Q9QUM0 |
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| Catalog # | MA5-16875 |
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| Price | |
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| Order / More Info | CD41 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26173808, 27573814 |
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| 产品资料 |
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