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| Product Name | GS 143 |
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| Description | β-TrCP1 ligase inhibitor. Inhibits IκBα ubiquitination (IC50 = 5.2 μM) without affecting proteasome activity. Blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells. Suppresses antigen-induced NFκB expression, inflammation and mucus production in airways of OVA-sensitized mice. Purity 98%. MW (observed): 466.46 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid |
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| Gene, Accession, CAS # | CAS: 916232-21-8 |
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| Catalog # | 5636/10 |
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| Order / More Info | GS 143 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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