| 产品详情 |
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| Product Name | Edoxaban (tosylate) |
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| Description | An orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively); >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin; prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma; reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis when administered at doses ranging from 0.5-12.5 mg/kg; reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DU-176b |
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| Gene, Accession, CAS # | CAS: 480449-71-6 |
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| Catalog # | 24030-5 |
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| Order / More Info | Edoxaban (tosylate) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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