| 产品详情 |
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| Antigenic Specificity | EPM2A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 0.25-0.50 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EPM2A Polyclonal Antibody. EPM2A/Laforin is a novel dual-specificity phosphatase which associates with polyribosomes and belongs to the protein-tyrosine phosphatase family. Two isoforms of Laforin are reported which have alternate C termini and a common segment that consists of a carbohydrate-binding module and a dual-specificity protein phosphatase domain. Laforin plays an important role in the regulation of glycogen metabolism, prevents the formation of polyglucasans, and hydrolyze phosphotyrosine and phosphoserine/threonine substrates. Malin, a ubiquitin ligase, helps in regulation of Laforin protein concentration. Laforin not only interacts with itself but also with PPP1R5, HIRIP5 and EPM2AIP1. Mutations in the gene encoding EPM2A have |
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| Immunogen | n/a |
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| Other Names | RP1-28C20.2, EPM2, MELF, LAFPTPase, epilepsy, progressive myoclonus type 2, Lafora disease (laforin), lafora PTPase, laforin |
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| Gene, Accession # | Entrez: 526888, 7957; Uniprot: B3EWF7 |
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| Catalog # | PA5-23252 |
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| Price | |
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| Order / More Info | EPM2A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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