| 产品详情 |
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| Antigenic Specificity | SIRP alpha |
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| Clone | 15-414 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 Tests |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: Neat |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIRP alpha Monoclonal Antibody (15-414), PE. CD172a, also known as signal-regulatory protein alpha, is a receptor-type transmembrane glycoprotein expressed on cells of myeloid origin, including granulocytes, dendritic cells (DCs), macrophages, mast cells and haematopoietic stem cells. CD172a acts as a substrate for several activated tyrosine kinases, including EGFR, PDGFR, src and insulin receptor and is involved in the negative regulation of receptor tyrosine kinase-coupled signaling pathways. Ligand binding of CD172a to integrin-associated protein CD47, results in tyrosine kinase phosphorylation of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within the cytoplasmic region of CD172a, mediating the recruitment and activation of t |
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| Immunogen | n/a |
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| Other Names | BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2, CD172 alpha |
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| Gene, Accession # | Entrez: 140885; Uniprot: P78324 |
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| Catalog # | MA1-74228 |
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| Price | |
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| Order / More Info | SIRP alpha Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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