| 产品详情 |
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| Antigenic Specificity | SIRT1 |
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| Clone | 1F3 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIRT1 Monoclonal Antibody (1F3). This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
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| Immunogen | n/a |
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| Other Names | SIR2L1; SIRT1 |
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| Gene, Accession # | Entrez: 23411; Uniprot: Q96EB6 |
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| Catalog # | MA5-15677 |
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| Price | |
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| Order / More Info | SIRT1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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