| 产品详情 |
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| Product Name | Bay 11-7821 |
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| Description | E2 ubiquitin (Ub) conjugating enzyme inhibitor. Inhibits the conjugation of Ub to a range of E2 enzymes. Inhibits E2 enzyme mediated IκBα phosphorylation and indirectly decreases NF-κb activity. Also reversibly activates MAPK signaling. Induces apoptosis of leukemic T cell and B-cell lymphoma cell lines. Also inhibits activation of NLRP3 inflammasome. Purity 99%. MW (observed): 207.25 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile. Bay 11-7082 |
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| Gene, Accession, CAS # | CAS: 19542-67-7 |
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| Catalog # | 1744/10 |
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| Price | |
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| Order / More Info | Bay 11-7821 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21705340, 24616502, 25257174, 25398056, 29070054, 29175508 |
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